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  • 使蒂諾斯可能導致夢遊

    根據印度醫師發表於近期出刊之International Medical Journal of Eating Disorders上之文章,發現有一名印度民眾連續服用含Zolpidem成分藥品,服藥後第10天夜晚 ,家人發現他不自知的夢遊到離家2公里外的店鋪大吃甜食,這名病患停止服安眠藥後,未再出現夢遊症狀。醫師認為,這樣的夢遊行為與其正服用的Zolpidem藥品有關。

    澳洲TGA也曾於2008年2月21日發布加強含zolpidem成分之鎮靜、安眠劑類藥品(商品名:使蒂諾斯,Stilnox)之仿單標示,標示之警語內容為病患服用該藥品後可能出現怪異之行為(夢遊走路、開車或吃 食物…等)而使病患暴露於危險情況。

    經查,衛生署核准使蒂諾斯藥品之適應症為「失眠症」,其列屬於醫師處方及第4級管制藥品,病患必需經由醫師 診治後才能夠開立處方,並應遵循處方服用。衛生署曾於96年3月15日與97年2月25日發布新聞提醒醫師 及病患使用鎮靜、安眠藥品應小心監視其引起夢遊或行為怪異之不良反應,且該類經衛生署審慎評估其風險效益後,於96年7月30日衛署 藥字第0960326114號公告鎮靜安眠藥仿單加刊「服用本品可能出現夢遊行為,例如開車、打電話及準備或食用食物」之警語。

    衛生署呼籲醫師為睡眠障礙病患處方鎮靜、安眠藥品時應審慎評估其用藥之風險與效益,同時宜提醒病患家屬或其健康照護者嚴密監視病患服藥後之情形。過年期間, 倘若飲酒也應避免與鎮定安眠藥品一起服用,以免導致嚴重不良反應。

     
     
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  • 減肥藥是什麼

    醫生處方的減肥藥的確可以輔助減重,但需要經醫生指導服用,避免胡亂自行購買服用。許多人對減肥藥的種類、原理及副作用一知 半解,導致濫用或效果未如預期。本文將詳細介紹減肥藥的定義、種類、原理、效果、常見成分、副作用、注意事 項,以及改善飲食與運動是否比服藥更好。

    減肥藥是指用於幫助減少體重或體脂的藥物或保健品,旨在通過影響代謝、食慾或脂肪吸收來達到瘦身效果。一般而言, 減肥藥可大致分類為處方藥(經註冊西醫處方的藥物)及非處方藥(如市售減肥保健品)需用於BMI≥30的肥 胖患者,或BMI≥27伴有併發症者。

    定義:減肥藥是經科學驗證或傳統使用的物質,輔助飲食及運動減重,非獨立解決方案。
    歷史:減肥藥可追溯至20世紀初,如安非他命類藥物,現代藥物更注重安全,如GLP-1受體激動劑。
    須留意的是,減肥藥不是「仙丹」,即使服用亦需要結合生活方式改變,長期服用者亦建議由註冊醫生監測身體狀 況。

    減肥藥種類多樣,根據作用機制分類,主要種類包括:

    食慾抑制劑:如Phentermine,抑制腦部饑餓信號,減少進食量。適合食慾旺盛者。
    脂肪吸收抑制劑:如Orlistat(Xenical),阻礙腸道吸收脂肪,排出多餘油脂。適合高脂飲食者。
    代謝促進劑:如綠茶萃取或咖啡因保健品,研究顯示可輕微增加產熱與能量消耗,但對體重的效果小且不穩定;多 見於非處方保健品,效果不及藥物。
    GLP-1受體激動劑:如Semaglutide(Ozempic),模擬腸道激素,延緩胃排空並降低食慾。屬於近 年最熱門的種類。
    其他:如Bupropion/Naltrexone組合,影響腦部獎勵系統,但務必注意禁忌與不良反應。
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